KAZN, kazrin, periplakin interacting protein

KAZN, kazrin, periplakin interacting protein

• This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]

• Gene Synonyms (C1orf196, KAZ, kazrin,)
• NCBI Gene ID: 23254
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q674X7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

kazrin, periplakin interacting protein interacts with:

• clavesin 2
  leucine zipper tumor suppressor 2
  ring finger protein 123
  tensin 4
  thioredoxin 2
  WD repeat domain 77

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.