EXPH5, exophilin 5

EXPH5, exophilin 5

• The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

• Gene Synonyms (SLAC2-B, SLAC2B, exophilin-5, slp homolog lacking C2 domains b, synaptotagmin-like homologue lacking C2 domains b, synaptotagmin-like protein homolog lacking C2 domains b,)
• NCBI Gene ID: 23086
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4E1U8
  UNIPROT ID#>>Q6AI59
  UNIPROT ID#>>B4E2C3
  UNIPROT ID#>>Q8NEV8
  UNIPROT ID#>>Q149M6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

exophilin 5 interacts with:

• heat shock protein family B (small) member 8
  hepatitis A virus cellular receptor 2
  non-SMC condensin II complex subunit H2
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.