PLCH1, phospholipase C eta 1

PLCH1, phospholipase C eta 1

• PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009]

• Gene Synonyms (PLC eta 1, PLC-L3, PLCL3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1, PLC-eta-1, phosphoinositide phospholipase C-eta-1, phospholipase C-eta1a, phospholipase C-eta1b, phospholipase C-like 3, phospholipase C-like protein 3,)
• NCBI Gene ID: 23007
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q4KWH8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase C eta 1 interacts with:

• chromosome 6 open reading frame 141
  egl-9 family hypoxia inducible factor 3
  F-box and WD repeat domain containing 11
  hypoxia inducible factor 1 subunit alpha inhibitor
  interleukin 17 receptor A
  pleckstrin homology domain containing A4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.