ARHGEF15, Rho guanine nucleotide exchange factor 15

ARHGEF15, Rho guanine nucleotide exchange factor 15

• Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene. [provided by RefSeq, Aug 2010]

• Gene Synonyms (ARGEF15, E5, Ephexin5, Vsm-RhoGEF, rho guanine nucleotide exchange factor 15, Rho guanine nucleotide exchange factor (GEF) 15, ephexin-5,)
• NCBI Gene ID: 22899
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94989
  UNIPROT ID#>>A0A0S2Z547
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho guanine nucleotide exchange factor 15 interacts with:

• centrosomal protein 55
  chromosome 11 open reading frame 49
  DnaJ heat shock protein family (Hsp40) member C5
  golgi reassembly stacking protein 2
  MOB family member 4, phocein
  SH3 domain containing ring finger 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.