UCMA, upper zone of growth plate and cartilage matrix associated

UCMA, upper zone of growth plate and cartilage matrix associated

• This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

• Gene Synonyms (unique cartilage matrix-associated protein, Gla-rich protein, C10orf49, GRP, GRP/UCMA,)
• NCBI Gene ID: 221044
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A067XJP8
  UNIPROT ID#>>A0A067XJX6
  UNIPROT ID#>>A0A067XKV3
  UNIPROT ID#>>Q8WVF2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

upper zone of growth plate and cartilage matrix associated interacts with:

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