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SENP5, SUMO specific peptidase 5

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SENP5, SUMO specific peptidase 5

  • The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]

  • Gene Synonyms (sentrin-specific protease 5, SUMO1/sentrin specific peptidase 5, SUMO1/sentrin specific protease 5, sentrin/SUMO-specific protease SENP5,)
  • NCBI Gene ID: 205564
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q96HI0
    UNIPROT ID#>>B2R9F5
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SUMO specific peptidase 5 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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