NLRC3, NLR family CARD domain containing 3

NLRC3, NLR family CARD domain containing 3

• This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

• Gene Synonyms (NLR family CARD domain-containing protein 3, CARD15-like protein, NACHT, LRR and CARD domains-containing protein 3, NOD-like receptor C3, caterpiller protein 16.2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3, CLR16.2, NOD3,)
• NCBI Gene ID: 197358
• Species: Homo sapiens (Human)
• UNIPROT ID#>>C3VPR7
  UNIPROT ID#>>Q7RTR2
  UNIPROT ID#>>Q8NF06
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NLR family CARD domain containing 3 interacts with:

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