Nfkbib, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

Nfkbib, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

• This gene encodes an inhibitor of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB). The encoded protein prevents NF-kappaB-mediated transcription activation by sequestering it in the cytosol. In response to signals that induce NF-kappaB, such as cytokines and growth factors, the encoded protein undergoes phosphorylation, triggering its rapid ubiquitination and proteasomal degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• (No alternate names found)
• NCBI Gene ID: 18036
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q60778
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta interacts with:

• v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.