SPTSSA, serine palmitoyltransferase small subunit A

SPTSSA, serine palmitoyltransferase small subunit A

• Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]

• Gene Synonyms (serine palmitoyltransferase small subunit A, small subunit of serine palmitoyltransferase A, C14orf147, SSSPTA,)
• NCBI Gene ID: 171546
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q969W0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine palmitoyltransferase small subunit A interacts with:

• cysteine rich tail 1
  protein prenyltransferase alpha subunit repeat containing 1
  transmembrane protein 31

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.