XAGE3, X antigen family member 3

XAGE3, X antigen family member 3

• This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]

• Gene Synonyms (X antigen family member 3, CT12.3, G antigen, family D, 4, cancer/testis antigen 12.3, cancer/testis antigen family 12, member 3a, cancer/testis antigen family 12, member 3b, g antigen family D member 4, placenta-specific 6, placenta-specific gene 6 protein, protein XAGE-3, CT12.3a, CT12.3b, GAGED4, PLAC6, XAGE-3, pp9012,)
• NCBI Gene ID: 170626
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WTP9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

X antigen family member 3 interacts with:

• late cornified envelope 2C
  methionyl aminopeptidase type 1D, mitochondrial

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.