DHX36, DEAH-box helicase 36

DHX36, DEAH-box helicase 36

• This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ATP-dependent DNA/RNA helicase DHX36, ATP-dependent RNA helicase DHX36, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36, DEAD/H box polypeptide 36, DEAH (Asp-Glu-Ala-His) box polypeptide 36, DEAH box protein 36, G4 resolvase-1, MLE-like protein 1, RNA helicase associated with AU-rich element ARE, RNA helicase associated with AU-rich element protein, probable ATP-dependent RNA helicase DHX36, DDX36, G4R1, MLEL1, RHAU,)
• NCBI Gene ID: 170506
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H2U1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DEAH-box helicase 36 interacts with:

• centrosomal protein 85-like
  mindbomb E3 ubiquitin protein ligase 1
  RPTOR independent companion of MTOR complex 2
  zinc finger and BTB domain containing 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.