AGR3, anterior gradient 3, protein disulphide isomerase family member

AGR3, anterior gradient 3, protein disulphide isomerase family member

• This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]

• Gene Synonyms (anterior gradient protein 3, anterior gradient homolog 3, anterior gradient protein 3 homolog, breast cancer membrane protein 11, protein disulfide isomerase family A, member 18, AG-3, AG3, BCMP11, HAG3, PDIA18, hAG-3,)
• NCBI Gene ID: 155465
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TD06
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

anterior gradient 3, protein disulphide isomerase family member interacts with:

• keratin associated protein 11-1

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