CCBE1, collagen and calcium binding EGF domains 1

CCBE1, collagen and calcium binding EGF domains 1

• This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010]

• Gene Synonyms (HKLLS1, collagen and calcium-binding EGF domain-containing protein 1, full of fluid protein homolog,)
• NCBI Gene ID: 147372
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6UXH8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collagen and calcium binding EGF domains 1 interacts with:

• inhibitor of CDK, cyclin A1 interacting protein 1
  keratin 27

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.