CD109, CD109 molecule

CD109, CD109 molecule

• This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

• Gene Synonyms (CPAMD7, p180, r150, CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Gov platelet alloantigens, activated T-cell marker CD109, platelet-specific Gov antigen,)
• NCBI Gene ID: 135228
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6YHK3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD109 molecule interacts with:

• ectonucleotide pyrophosphatase/phosphodiesterase 7
  filamin, beta
  gap junction protein beta 7
  interferon epsilon
  odontogenesis associated phosphoprotein
  ribonuclease A family member 13 (inactive)
  ring finger protein 38
  secretoglobin family 1D member 4
  serine protease 33
  serine protease 37

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.