Cebpa, CCAAT/enhancer binding protein (C/EBP), alpha

Cebpa, CCAAT/enhancer binding protein (C/EBP), alpha

• This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. The use of alternative in-frame non-AUG (CUG) and AUG start codons results in several protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the CUG and the first AUG start codons. [provided by RefSeq, Sep 2014]

• (No alternate names found)
• NCBI Gene ID: 12606
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>P53566
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CCAAT/enhancer binding protein (C/EBP), alpha interacts with:

• apoptotic chromatin condensation inducer 1
  bromodomain adjacent to zinc finger domain 1A
  CCAAT/enhancer binding protein (C/EBP), beta
  CCAAT/enhancer binding protein zeta
  DEAD box helicase 1
  DEAD box helicase 18
  DEAD box helicase 47
  DEAD box helicase 54
  dihydrolipoamide branched chain transacylase E2
  DNA segment, Chr 1, Pasteur Institute 1
  DNA-damage inducible transcript 3
  E1A binding protein p300
  eukaryotic translation initiation factor 2, subunit 1 alpha
  eukaryotic translation initiation factor 4A3
  Ewing sarcoma breakpoint region 1
  exportin 1
  FtsJ RNA methyltransferase homolog 3 (E. coli)
  granzyme B
  guanine nucleotide binding protein (G protein), beta 2
  H2A.Z variant histone 1
  HDGF like 2
  heat shock protein 5
  heterochromatin protein 1, binding protein 3
  heterogeneous nuclear ribonucleoprotein M
  heterogeneous nuclear ribonucleoprotein U-like 2
  histone deacetylase 1
  histone deacetylase 2
  integrator complex subunit 13
  integrator complex subunit 7
  Jun dimerization protein 2
  karyopherin (importin) beta 1
  lamin B receptor
  lamin B1
  ligase III, DNA, ATP-dependent
  mannosyl-oligosaccharide glucosidase
  matrin 3
  mediator complex subunit 23
  metastasis-associated gene family, member 2
  minichromosome maintenance complex component 4
  minichromosome maintenance complex component 7
  myosin, heavy polypeptide 9, non-muscle
  myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
  N-acetyltransferase 10
  NOC2 like nucleolar associated transcriptional repressor
  NOP56 ribonucleoprotein
  NOP58 ribonucleoprotein
  nuclear receptor coactivator 3
  nuclear receptor coactivator 5
  nuclear RNA export factor 1
  nucleolar protein 10
  nucleolar protein family 6 (RNA-associated)
  nucleoporin 107
  nucleoporin 160
  nucleoporin 93
  O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
  pinin
  polymerase (RNA) II (DNA directed) polypeptide A
  pre-mRNA processing factor 4
  programmed cell death 11
  proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  protein phosphatase 2, regulatory subunit A, alpha
  pumilio RNA-binding family member 3
  pyrroline-5-carboxylate reductase family, member 2
  RAD21 cohesin complex component
  RB transcriptional corepressor 1
  RB transcriptional corepressor like 1
  replication factor C (activator 1) 2
  replication factor C (activator 1) 3
  replication factor C (activator 1) 4
  ribophorin I
  ribophorin II
  ribosomal protein L27
  ribosomal protein S14
  ribosomal protein S25
  ribosomal protein S3
  ribosomal protein S4, X-linked
  ribosomal protein S9
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ribosomal RNA processing 12 homolog (S. cerevisiae)
  RNA binding motif protein 39
  RNA binding protein with serine rich domain 1
  scaffold attachment factor B2
  serine and arginine-rich splicing factor 3
  serine and arginine-rich splicing factor 5
  SHANK-associated RH domain interacting protein
  Sin3-associated polypeptide 18
  small nuclear ribonucleoprotein 70 (U1)
  smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
  spectrin alpha, non-erythrocytic 1
  spectrin beta, non-erythrocytic 1
  SRY (sex determining region Y)-box 8
  stromal antigen 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  THO complex 1
  THO complex 5
  topoisomerase (DNA) I
  topoisomerase (DNA) II alpha
  transcription elongation regulator 1 (CA150)
  transcription factor 7 like 2, T cell specific, HMG box
  transcriptional regulator, SIN3A (yeast)
  tribbles pseudokinase 1
  tribbles pseudokinase 2
  ubiquitin specific peptidase 39
  URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
  valosin containing protein
  WD repeat domain 5
  Wilms tumour 1-associating protein
  zinc finger RNA binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.