OSCAR, osteoclast associated Ig-like receptor

OSCAR, osteoclast associated Ig-like receptor

• Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

• Gene Synonyms (PIGR3, PIgR-3, osteoclast-associated immunoglobulin-like receptor, osteoclast associated receptor OSCAR-S1, osteoclast associated receptor OSCAR-S2, osteoclast associated, immunoglobulin-like receptor, poly-Ig receptor 3, polymeric immunoglobulin receptor 3,)
• NCBI Gene ID: 126014
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0A0MRF2
  UNIPROT ID#>>A0A087X1R2
  UNIPROT ID#>>A0A0A0MR14
  UNIPROT ID#>>A0A087WV17
  UNIPROT ID#>>Q8IYS5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

osteoclast associated Ig-like receptor interacts with:

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