TWIST2, twist family bHLH transcription factor 2

TWIST2, twist family bHLH transcription factor 2

• The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]

• Gene Synonyms (AMS, BBRSAY, DERMO1, FFDD3, SETLSS, bHLHa39, twist-related protein 2, class A basic helix-loop-helix protein 39, dermis-expressed protein 1, twist basic helix-loop-helix transcription factor 2, twist homolog 2, twist-related bHLH protein Dermo1,)
• NCBI Gene ID: 117581
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WVJ9
  UNIPROT ID#>>A0A024R4D4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

twist family bHLH transcription factor 2 interacts with:

• Fer3 like bHLH transcription factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.