- Gene Overview
- Interaction Network
- Sequence Verification
ARAP1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
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The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
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Gene Synonyms (CENTD2, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1, centaurin-delta-2, cnt-d2,)
- NCBI Gene ID:
116985
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q96P48
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 interacts with:
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