- Gene Overview
- Interaction Network
- Sequence Verification
SLC22A12, solute carrier family 22 member 12
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The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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Gene Synonyms (OAT4L, RST, URAT1, solute carrier family 22 member 12, organic anion transporter 4-like protein, renal-specific transporter, solute carrier family 22 (organic anion/cation transporter), member 12, solute carrier family 22 (organic anion/urate transporter), member 12, urate anion exchanger 1, urate transporter 1,)
- NCBI Gene ID:
116085
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q96S37
UNIPROT ID#>>B3KP53
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
solute carrier family 22 member 12 interacts with:
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