PLCD3, phospholipase C delta 3

PLCD3, phospholipase C delta 3

• This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]

• Gene Synonyms (PLC-delta-3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3, PLC delta3, phosphoinositide phospholipase C-delta-3,)
• NCBI Gene ID: 113026
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N3E9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase C delta 3 interacts with:

• G protein-coupled receptor 156

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