STX1B, syntaxin 1B

STX1B, syntaxin 1B

• The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]

• Gene Synonyms (GEFSP9, STX1B1, STX1B2, syntaxin-1B, syntaxin-1B1, syntaxin-1B2,)
• NCBI Gene ID: 112755
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61266
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

syntaxin 1B interacts with:

• FAM161 centrosomal protein B
  family with sequence similarity 209 member A
  family with sequence similarity 81 member A
  G protein-coupled receptor 152
  synaptosome associated protein 47
  taxilin alpha

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.