- Gene Overview
- Interaction Network
- Sequence Verification
GTF3C6, general transcription factor IIIC subunit 6
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RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008]
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Gene Synonyms (C6orf51, TFIIIC35, bA397G5.3, general transcription factor 3C polypeptide 6, TFIIIC 35 kDa subunit, general transcription factor IIIC, polypeptide 6, alpha 35kDa, transcription factor IIIC 35 kDa subunit, transcription factor IIIC 35kDa, transcription factor IIIC subunit 6,)
- NCBI Gene ID:
112495
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q969F1
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
general transcription factor IIIC subunit 6 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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