NUDT6, nudix hydrolase 6

NUDT6, nudix hydrolase 6

• This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (nucleoside diphosphate-linked moiety X motif 6, antisense basic fibroblast growth factor, nudix (nucleoside diphosphate linked moiety X)-type motif 6, ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1,)
• NCBI Gene ID: 11162
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P53370
  UNIPROT ID#>>B4DG76
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nudix hydrolase 6 interacts with:

• bolA family member 3
  iron-sulfur cluster assembly 1
  metabolism of cobalamin associated B
  peptidase M20 domain containing 2
  tubulointerstitial nephritis antigen
  ubiquitin like domain containing CTD phosphatase 1
  ubiquitin protein ligase E3 component n-recognin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.