- Gene Overview
- Interaction Network
- Sequence Verification
EDAR, ectodysplasin A receptor
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This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
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Gene Synonyms (DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, tumor necrosis factor receptor superfamily member EDAR, EDA-A1 receptor, anhidrotic ectodysplasin receptor 1, downless homolog, downless, mouse, homolog of, ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor,)
- NCBI Gene ID:
10913
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9UNE0
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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ectodysplasin A receptor interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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