Skip Navigation Links Home » Resources » Gene Detail

CERS1, ceramide synthase 1

Matching ORF Clones

    No catalog ORF clones available (link to the custom ORF request form)

Request a Custom Clone

Don't see what you need?

Request My Custom Clone »
  • Gene Overview
  • Interaction Network
  • Sequence Verification

CERS1, ceramide synthase 1

  • This gene encodes a ceramide synthase enzyme, which catalyzes the synthesis of ceramide, the hydrophobic moiety of sphingolipids. The encoded enzyme synthesizes 18-carbon (C18) ceramide in brain neurons. Elevated expression of this gene may be associated with increased longevity, while decreased expression of this gene may be associated with myoclonus epilepsy with dementia in human patients. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2016]

  • Gene Synonyms (EPM8, GDF-1, GDF1, LAG1, LASS1, UOG1, ceramide synthase 1, Embryonic growth/differentiation factor 1, longevity assurance (LAG1, S. cerevisiae) homolog 1, longevity assurance gene 1 protein homolog 1, protein UOG-1, upstream of GDF1,)
  • NCBI Gene ID: 10715
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>P27544
    UNIPROT ID#>>B4DE47
    UNIPROT ID#>>Q5XG75
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ceramide synthase 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.