FUT9, fucosyltransferase 9

FUT9, fucosyltransferase 9

• The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]

• Gene Synonyms (Fuc-TIX, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, alpha-(1,3)-fucosyltransferase 9, fucT-IX, fucosyltransferase 9 (alpha (1,3) fucosyltransferase), fucosyltransferase IX, galactoside 3-L-fucosyltransferase,)
• NCBI Gene ID: 10690
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y231
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fucosyltransferase 9 interacts with:

• FKBP prolyl isomerase 14
  golgi membrane protein 1
  heat shock transcription factor 2 binding protein
  lipase maturation factor 1
  OS9 endoplasmic reticulum lectin
  testis specific serine kinase 3
  zinc finger DHHC-type palmitoyltransferase 17

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.