CRTAP, cartilage associated protein

CRTAP, cartilage associated protein

• The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CASP, LEPREL3, OI7, P3H5, cartilage-associated protein, leprecan-like 3, prolyl 3-hydroxylase family member 5 (non-enzymatic),)
• NCBI Gene ID: 10491
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75718
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cartilage associated protein interacts with:

• armadillo repeat containing 9
  cleavage stimulation factor subunit 2 tau variant
  coiled-coil domain containing 120
  DISC1 scaffold protein
  EMI domain containing 1
  factor interacting with PAPOLA and CPSF1
  F-box protein 6
  GPN-loop GTPase 1
  innate immunity activator
  MAP3K12 binding inhibitory protein 1
  MIA SH3 domain ER export factor 3
  mitochondria localized glutamic acid rich protein
  nudix hydrolase 21
  pleckstrin homology domain containing A4
  prolyl 3-hydroxylase 1
  RAD18 E3 ubiquitin protein ligase
  RNA binding protein with serine rich domain 1
  serine and arginine-rich splicing factor 1
  SH3 domain containing GRB2 like, endophilin B2
  splicing factor 3a, subunit 1
  testin LIM domain protein
  TNFAIP3 interacting protein 2
  TSC22 domain family member 4
  VPS37D subunit of ESCRT-I
  WD repeat domain 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.