DPP3, dipeptidyl peptidase 3

DPP3, dipeptidyl peptidase 3

• This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]

• Gene Synonyms (dipeptidyl peptidase 3, DPP III, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, dipeptidyl peptidase III, enkephalinase B, DPPIII,)
• NCBI Gene ID: 10072
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JPB8
  UNIPROT ID#>>Q9NY33
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dipeptidyl peptidase 3 interacts with:

• aldehyde dehydrogenase 8 family member A1
  anterior gradient 2, protein disulphide isomerase family member
  destrin, actin depolymerizing factor
  NHL repeat containing 2
  N-myc downstream regulated 1
  protection of telomeres 1
  TERF1 interacting nuclear factor 2
  TERF2 interacting protein
  TNF alpha induced protein 8
  transport and golgi organization 2 homolog

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.