AAV-NanoLuc® Transduction Inhibition Assay

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT.

This material may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for

• (1) research use,
• (2) discovery, development and monitoring of biologic drugs and vaccines,
• (3) quality assurance testing of biologic drugs and vaccines, and
• (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed.

"Commercial use” means any and all uses of this material by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this material for any use. Recipient has no right to modify or otherwise create variations of the virus or nucleotide sequence of the luciferase gene. In addition, recipient must use a Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this material, or contact Promega to obtain a license for use of this material with reagents other than Promega’s.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS MATERIAL. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Promega Cell Line Limited Use Label License (LULL)

BY USE OF THIS MATERIAL, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE.

• 1. Usage and Transfer Restrictions:
  • 1.1. Recipient may use this material for research use only, which includes but is not limited to drug discovery and development, quality assurance testing and product release assays. No transfer, resale or commercial use of this material is allowed without the written consent of Promega Corporation.
  • 1.2. “Commercial use” means any and all uses of this material or derivatives by recipient for monetary or other consideration, including product manufacture, providing a service, information or data to unaffiliated third parties and resale of the material for any use.
• 2. Modification Restrictions:
  • 2.1. Recipient shall have no right to modify, derivatize or otherwise create variations of the nucleotide sequence of any proprietary gene, including but not limited to luciferase, NanoBiT® technology (e.g., HiBiT), HaloTag® technology or genes stably transfected within the cells.
  • 2.2. Recipient shall have no right to genetically engineer or otherwise modify the cell line.
• 3. Propagation and Storage:
  • 3.1. The recipient may not propagate the cells, unless material is marked as Propagation Model, Cell Bank or Master Cell Bank; then recipient may propagate and store the cells for long-term use.
• 4. For all determinations of luminescence or other assay-related activity of this material and its derivatives, recipient must either:
  • 4.1. Use the detection systems specified in the protocol or data report and purchased from Promega for all luminescence assays when using this material; or
  • 4.2. Contact Promega to obtain a license for use of this material with reagents other than a Bio-Glo™ branded luciferase reagent, including but not limited to:
    • 4.2.1 Bio-Glo™, Bio-Glo-NL™, Bio-Glo-NB™ TCK, Bio-Glo-NB™ VLP, Bio-Glo-NB™ Lytic
• 5. For uses of this material for energy transfer (such as bioluminescence resonance energy transfer), recipient must:
  • 5.1. Use NanoBRET™-branded luminescent assay reagents (LARs; e.g., NanoBRET™ Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine™/Inhibitor for all determinations of luminescent activity by this material and its derivatives; and
  • 5.2. Use NanoBRET™-branded energy acceptors (e.g., NanoBRET™ tracers, NanoBRET™ dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this material and its derivatives; or
  • 5.3. Contact Promega to obtain a license for the use of the material and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.
• 6. For uses of HaloTag® Technology in this material, recipient must either:
  • 6.1. Use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties; or
  • 6.2. Contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.
• 7. Disclaimer and Governing Law:
  • 7.1. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE MATERIAL. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.