CD14, CD14 molecule

CD14, CD14 molecule

• The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]

• Gene Synonyms (monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein,)
• NCBI Gene ID: 929
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08571
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD14 molecule interacts with:

• 2'-5'-oligoadenylate synthetase like
  adaptor related protein complex 3 subunit sigma 1
  ADP ribosylation factor GTPase activating protein 3
  AT-rich interaction domain 2
  BCAS3 microtubule associated cell migration factor
  CD55 molecule (Cromer blood group)
  exonuclease 1
  galectin 3 binding protein
  gap junction protein beta 2
  HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
  integrin subunit beta 2
  intercellular adhesion molecule 5
  interleukin 1 receptor associated kinase 3
  lactotransferrin
  lipopolysaccharide binding protein
  PHD finger protein 20 like 1
  PHD finger protein 21A
  protein phosphatase 1 regulatory subunit 12B
  protein phosphatase 3 regulatory subunit B, beta
  RNA polymerase II subunit J
  supervillin
  TATA-box binding protein associated factor 1
  TATA-box binding protein associated factor 9
  TNF receptor superfamily member 1B
  toll like receptor 2
  toll like receptor 3
  toll like receptor 4
  WD repeat and coiled coil containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.