CBR3, carbonyl reductase 3

CBR3, carbonyl reductase 3

• Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

• Gene Synonyms (carbonyl reductase [NADPH] 3, NADPH-dependent carbonyl reductase 3, carbonyl reductase (NADPH) 3, epididymis secretory protein Li 25, short chain dehydrogenase/reductase family 21C member 2, HEL-S-25, SDR21C2, hCBR3,)
• NCBI Gene ID: 874
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75828
  UNIPROT ID#>>V9HW40
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carbonyl reductase 3 interacts with:

• ariadne RBR E3 ubiquitin protein ligase 2
  ATP binding cassette subfamily E member 1
  BICD cargo adaptor 2
  BTB domain containing 9
  cyclin L2
  defective in cullin neddylation 1 domain containing 1
  E74 like ETS transcription factor 3
  EWS RNA binding protein 1
  low density lipoprotein receptor
  marker of proliferation Ki-67
  NADH:ubiquinone oxidoreductase core subunit S3
  pleckstrin homology domain containing A4
  RAB interacting factor
  RAB35, member RAS oncogene family
  ribosomal protein S10
  RIO kinase 1
  SHANK associated RH domain interactor
  syndecan binding protein
  ubiquitin C
  ubiquitin specific peptidase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.