CAPG, capping actin protein, gelsolin like

CAPG, capping actin protein, gelsolin like

• This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (macrophage-capping protein, actin-regulatory protein CAP-G, capping protein (actin filament), gelsolin-like, epididymis secretory protein Li 66, gelsolin-like capping protein, AFCP, HEL-S-66, MCP,)
• NCBI Gene ID: 822
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P40121
  UNIPROT ID#>>B2R9S4
  UNIPROT ID#>>V9HW69
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

capping actin protein, gelsolin like interacts with:

• cadherin 1
  cell division cycle 5 like
  cofilin 1
  coiled-coil domain containing 88A
  cyclin dependent kinase 15
  cyclin Y like 1
  cysteine rich protein 1
  DAZ associated protein 1
  DEAD-box helicase 19B
  DnaJ heat shock protein family (Hsp40) member C11
  electron transfer flavoprotein subunit beta
  far upstream element binding protein 1
  heat shock protein family A (Hsp70) member 8
  KH RNA binding domain containing, signal transduction associated 2
  kinesin family member 21B
  kinesin family member C1
  macrophage migration inhibitory factor
  non-SMC condensin I complex subunit H
  peroxiredoxin 6
  pirin
  siah E3 ubiquitin protein ligase 1
  SNW domain containing 1
  sorting nexin 3
  TBC1 domain family member 22B
  transketolase
  tumor protein p53
  ubiquitin fold modifier 1
  ubiquitin-fold modifier conjugating enzyme 1
  zinc finger and SCAN domain containing 20

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.