BOK, BCL2 family apoptosis regulator BOK

BOK, BCL2 family apoptosis regulator BOK

• The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]

• Gene Synonyms (bcl-2-related ovarian killer protein, BCL2 related ovarian killer, BOK, BCL2 family apoptosis regulator, bcl-2-like protein 9, bcl2-L-9, hBOK, BCL2L9, BOKL,)
• NCBI Gene ID: 666
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R4A8
  UNIPROT ID#>>Q9UMX3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BCL2 family apoptosis regulator BOK interacts with:

• estrogen receptor 2
  MCL1 apoptosis regulator, BCL2 family member
  MYC proto-oncogene, bHLH transcription factor
  nitric oxide associated 1
  thymocyte expressed, positive selection associated 1

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