CCL16, C-C motif chemokine ligand 16

CCL16, C-C motif chemokine ligand 16

• This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]

• Gene Synonyms (C-C motif chemokine 16, IL-10-inducible chemokine, chemokine (C-C motif) ligand 16, chemokine LEC, liver CC chemokine-1, liver-expressed chemokine, lymphocyte and monocyte chemoattractant, monotactin-1, new CC chemokine 4, small inducible cytokine subfamily A (Cys-Cys), member 16, small-inducible cytokine A16, CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4,)
• NCBI Gene ID: 6360
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15467
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-C motif chemokine ligand 16 interacts with:

• C-C motif chemokine receptor 2
  histamine receptor H4
  ubiquilin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.