ATP6V0B, ATPase H+ transporting V0 subunit b

ATP6V0B, ATPase H+ transporting V0 subunit b

• This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Gene Synonyms (V-type proton ATPase 21 kDa proteolipid subunit, ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b, ATPase, H+ transporting, lysosomal, 21-KD, V0 subunit C-prime, prime, ATPase, H+ transporting, lysosomal, subunit F, H(+)-transporting two-sector ATPase, subunit F, V-ATPase 21 kDa proteolipid subunit, V-ATPase subunit c'', vacuolar ATP synthase 21 kDa proteolipid subunit, vacuolar proton pump 21 kDa proteolipid subunit, ATP6F, HATPL, VMA16,)
• NCBI Gene ID: 533
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99437
  UNIPROT ID#>>E9PNL3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase H+ transporting V0 subunit b interacts with:

• adhesion G protein-coupled receptor G3
  collagen type IV alpha 5 chain
  epithelial membrane protein 1
  family with sequence similarity 210 member B
  G protein-coupled receptor 42
  G protein-coupled receptor 61
  gap junction protein alpha 8
  glucagon like peptide 1 receptor
  insulin induced gene 2
  interleukin 1 receptor associated kinase 3
  killer cell lectin like receptor C1
  major intrinsic protein of lens fiber
  melatonin receptor 1B
  membrane spanning 4-domains A3
  mitochondrial fission factor
  Mov10 RISC complex RNA helicase
  nuclear RNA export factor 1
  nurim
  solute carrier family 10 member 1
  solute carrier family 2 member 5
  sperm acrosome associated 1
  stomatin
  syntrophin alpha 1
  transmembrane 4 L six family member 19
  transmembrane protein 242
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  vacuolar ATPase assembly factor VMA21

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.