- Gene Overview
- Interaction Network
- Sequence Verification
DUOX2, dual oxidase 2
-
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]
-
Gene Synonyms (dual oxidase 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, dual oxidase-like domains 2, flavoprotein NADPH oxidase, large NOX 2, long NOX 2, nicotinamide adenine dinucleotide phosphate oxidase, p138 thyroid oxidase, thyroid oxidase 2, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2,)
- NCBI Gene ID:
50506
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>Q9NRD8
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
dual oxidase 2 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|