ATP4B, ATPase H+/K+ transporting subunit beta

ATP4B, ATPase H+/K+ transporting subunit beta

• The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]

• Gene Synonyms (potassium-transporting ATPase subunit beta, ATPase H+/K+ transporting beta subunit, ATPase, H+/K+ exchanging, beta polypeptide, ATPase, H+/K+ transporting, beta polypeptide, gastric H(+)/K(+) ATPase subunit beta, gastric H+/K+ ATPase beta subunit, gastric hydrogen-potassium ATPase, beta, potassium-transporting ATPase beta chain, proton pump beta chain, ATP6B,)
• NCBI Gene ID: 496
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P51164
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase H+/K+ transporting subunit beta interacts with:

• argonaute RISC catalytic component 3
  bisphosphoglycerate mutase
  cyclin D1 binding protein 1
  G protein-coupled receptor 42
  syntaxin 1A
  zinc finger C4H2-type containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.