ASNS, asparagine synthetase (glutamine-hydrolyzing)

ASNS, asparagine synthetase (glutamine-hydrolyzing)

• The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

• Gene Synonyms (asparagine synthetase [glutamine-hydrolyzing], TS11 cell cycle control protein, glutamine-dependent asparagine synthetase, ASNSD, TS11,)
• NCBI Gene ID: 440
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08243
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

asparagine synthetase (glutamine-hydrolyzing) interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  3'-phosphoadenosine 5'-phosphosulfate synthase 1
  activator of HSP90 ATPase activity 1
  AHNAK nucleoprotein
  aldehyde dehydrogenase 7 family member A1
  argininosuccinate synthase 1
  ataxin 1
  ATP binding cassette subfamily E member 1
  autophagy related 101
  BCL2 like 14
  calpain 2
  calpain small subunit 1
  CD2 associated protein
  CD74 molecule
  cleavage stimulation factor subunit 1
  clusterin associated protein 1
  Coenzyme A synthase
  COP9 signalosome subunit 5
  cyclin dependent kinase 2
  cyclin dependent kinase 9
  cystathionine beta-synthase
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 1
  DET1 and DDB1 associated 1
  dual specificity phosphatase 22
  dual specificity phosphatase 28
  epidermal growth factor receptor
  family with sequence similarity 78 member A
  fatty acid synthase
  glutamine--fructose-6-phosphate transaminase 1
  glutaminyl-tRNA synthetase 1
  glutamyl-prolyl-tRNA synthetase 1
  glutaredoxin
  glutathione synthetase
  glycyl-tRNA synthetase 1
  guanine deaminase
  heat shock protein family A (Hsp70) member 8
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 2
  HSPA (Hsp70) binding protein 1
  integrin subunit alpha 4
  interferon regulatory factor 2
  isochorismatase domain containing 1
  isoleucyl-tRNA synthetase 1
  kynureninase
  leucyl-tRNA synthetase 1
  limb development membrane protein 1 like
  lysophospholipase 1
  methionine adenosyltransferase 2A
  mitogen-activated protein kinase 3
  moesin
  MYC proto-oncogene, bHLH transcription factor
  myosin IE
  neurotrophic receptor tyrosine kinase 1
  NMD3 ribosome export adaptor
  NPL4 homolog, ubiquitin recognition factor
  nucleoporin 50
  Obg like ATPase 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  paxillin
  phosphatidylethanolamine binding protein 1
  phosphoglycerate dehydrogenase
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  platelet activating factor acetylhydrolase 1b regulatory subunit 1
  pleckstrin homology domain containing A4
  protein disulfide isomerase family A member 4
  protein kinase AMP-activated non-catalytic subunit gamma 2
  protein phosphatase 1 catalytic subunit alpha
  prothymosin alpha
  PTEN induced kinase 1
  pyridoxal phosphate binding protein
  RAD18 E3 ubiquitin protein ligase
  Rap1 GTPase-GDP dissociation stimulator 1
  RecQ like helicase 4
  ribonucleotide reductase regulatory subunit M2
  ring finger protein 123
  serine carboxypeptidase 1
  serine/threonine kinase 24
  serine/threonine kinase 26
  SH2 domain containing 4A
  sirtuin 7
  staufen double-stranded RNA binding protein 1
  striatin 4
  succinate dehydrogenase complex flavoprotein subunit A
  superoxide dismutase 1
  testin LIM domain protein
  tetratricopeptide repeat domain 27
  thyroid hormone receptor interactor 4
  TNF receptor associated protein 1
  tripartite motif containing 14
  tripartite motif containing 25
  tripartite motif containing 28
  tripartite motif containing 69
  tubulin folding cofactor B
  twinfilin actin binding protein 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  ubiquilin 1
  ubiquilin 4
  ubiquitin like modifier activating enzyme 1
  ubiquitin recognition factor in ER associated degradation 1
  UDP-galactose-4-epimerase
  vascular cell adhesion molecule 1
  vinculin
  WD repeat domain 27
  WW domain containing oxidoreductase
  X-prolyl aminopeptidase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.