HSD17B3, hydroxysteroid 17-beta dehydrogenase 3

HSD17B3, hydroxysteroid 17-beta dehydrogenase 3

• This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]

• Gene Synonyms (testosterone 17-beta-dehydrogenase 3, 17-beta-HSD 3, 17-beta-HSD3, 17-beta-hydroxysteroid dehydrogenase type 3, hydroxysteroid dehydrogenase 3, short chain dehydrogenase/reductase family 12C member 2, testicular 17-beta-hydroxysteroid dehydrogenase, EDH17B3, SDR12C2,)
• NCBI Gene ID: 3293
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P37058
  UNIPROT ID#>>Q6FH62
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hydroxysteroid 17-beta dehydrogenase 3 interacts with:

• actin beta like 2
  AHNAK nucleoprotein
  glycogen phosphorylase B
  HECT and RLD domain containing E3 ubiquitin protein ligase 3
  neuronal calcium sensor 1
  POTE ankyrin domain family member I
  protein phosphatase 1 catalytic subunit gamma
  Purkinje cell protein 2
  Tax1 binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.