SLC25A5, solute carrier family 25 member 5

SLC25A5, solute carrier family 25 member 5

• This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]

• Gene Synonyms (ADP/ATP translocase 2, ADP,ATP carrier protein, fibroblast isoform, adenine nucleotide translocator 2 (fibroblast), solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5, 2F1, AAC2, ANT2, T2, T3,)
• NCBI Gene ID: 292
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P05141
  UNIPROT ID#>>Q6NVC0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 25 member 5 interacts with:

• AAR2 splicing factor
  adaptor related protein complex 2 subunit mu 1
  ankyrin repeat and SOCS box containing 10
  ankyrin repeat and SOCS box containing 14
  ankyrin repeat and SOCS box containing 18
  ankyrin repeat and SOCS box containing 3
  ankyrin repeat and SOCS box containing 6
  annexin A11
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inducing factor mitochondria associated 1
  apurinic/apyrimidinic endodeoxyribonuclease 1
  A-Raf proto-oncogene, serine/threonine kinase
  argonaute RISC component 4
  ataxin 3
  ATP synthase membrane subunit DAPIT
  ATPase H+ transporting V0 subunit d1
  baculoviral IAP repeat containing 3
  BAG cochaperone 3
  bromodomain containing 7
  catenin beta 1
  CCCTC-binding factor
  cell division cycle 37, HSP90 cochaperone
  chromodomain helicase DNA binding protein 3
  chromodomain helicase DNA binding protein 4
  CLN3 lysosomal/endosomal transmembrane protein, battenin
  CLN5 intracellular trafficking protein
  clusterin associated protein 1
  coenzyme Q2, polyprenyltransferase
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  creatine kinase, mitochondrial 1A
  cryptochrome circadian regulator 1
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  cyclin D1
  cyclin dependent kinase 1
  cyclin dependent kinase 9
  cyclin J like
  CYLD lysine 63 deubiquitinase
  cytochrome c oxidase assembly homolog COX15
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 1
  DExD-box helicase 39B
  dickkopf WNT signaling pathway inhibitor 3
  dihydrolipoamide S-succinyltransferase
  egl-9 family hypoxia inducible factor 3
  ELAV like RNA binding protein 1
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  erb-b2 receptor tyrosine kinase 3
  estrogen receptor 1
  estrogen related receptor beta
  eukaryotic translation initiation factor 4A3
  ezrin
  FA complementation group D2
  Fas associated factor 1
  F-box protein 6
  F-box protein 7
  fibronectin 1
  FUS RNA binding protein
  galectin 3
  gigaxonin
  glyoxylate and hydroxypyruvate reductase
  growth factor receptor bound protein 2
  H4 clustered histone 1
  heat shock protein 90 alpha family class A member 1
  heat shock protein family A (Hsp70) member 8
  heat shock protein family B (small) member 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heparin binding growth factor
  heterogeneous nuclear ribonucleoprotein U
  HEXIM P-TEFb complex subunit 1
  hypoxia inducible factor 1 subunit alpha inhibitor
  inositol polyphosphate phosphatase like 1
  insulin like growth factor 1 receptor
  integrin alpha FG-GAP repeat containing 1
  integrin beta 1 (fibronectin receptor beta)
  integrin subunit alpha 4
  keratin 1
  keratin 17
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  lamin A/C
  leucine rich repeat containing G protein-coupled receptor 4
  mago homolog, exon junction complex subunit
  methylphosphate capping enzyme
  methyltransferase like 14
  minichromosome maintenance complex component 2
  minichromosome maintenance complex component 5
  mitochondrial ribosomal protein L58
  mitochondrial ribosomal protein S16
  mitochondrial ribosomal protein S34
  mitogen-activated protein kinase 6
  mitogen-activated protein kinase kinase 3
  MYC proto-oncogene, bHLH transcription factor
  NADH:ubiquinone oxidoreductase subunit S4
  neurofibromin 2
  neuroplastin
  neurotrophic receptor tyrosine kinase 1
  NFKB inhibitor alpha
  nicastrin
  nitric oxide synthase 2
  NOP56 ribonucleoprotein
  nuclear receptor subfamily 2 group C member 2
  nuclear transcription factor, X-box binding 1
  nucleophosmin 1
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  palmitoyl-protein thioesterase 1
  parkin RBR E3 ubiquitin protein ligase
  phosphatase and tensin homolog
  phosphomannomutase 2
  PIH1 domain containing 1
  pleckstrin homology domain containing A2
  pleckstrin homology domain containing A4
  poly(rC) binding protein 1
  pre-mRNA processing factor 8
  prohibitin
  protein kinase C zeta
  protein phosphatase, Mg2+/Mn2+ dependent 1A
  protein phosphatase, Mg2+/Mn2+ dependent 1E
  PTEN induced kinase 1
  RAB11A, member RAS oncogene family
  ras homolog family member A
  RE1 silencing transcription factor
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  ribophorin I
  ribosomal protein L10a
  ribosomal protein L11
  ribosomal protein L14
  ribosomal protein L15
  ribosomal protein L18
  ribosomal protein L19
  ribosomal protein L21
  ribosomal protein L23
  ribosomal protein L23a
  ribosomal protein L31
  ribosomal protein L37a
  ribosomal protein L4
  ribosomal protein L5
  ribosomal protein L6
  ribosomal protein L7
  ribosomal protein L7a
  ribosomal protein L9
  ribosomal protein S15a
  ribosomal protein S19
  ribosomal protein S2
  ribosomal protein S21
  ribosomal protein S23
  ribosomal protein S24
  ribosomal protein S28
  ribosomal protein S3
  ribosomal protein S3A
  ribosomal protein S4 X-linked
  ribosomal protein S6
  ribosomal protein S6 kinase B2
  ribosomal protein S8
  ribosomal protein SA
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 123
  ring finger protein 126
  ring finger protein 31
  ring finger protein 4
  ring-box 1
  SEC61 translocon subunit beta
  sirtuin 4
  SKI proto-oncogene
  SMAD family member 2
  SMAD specific E3 ubiquitin protein ligase 1
  SMAD specific E3 ubiquitin protein ligase 2
  snail family transcriptional repressor 1
  solute carrier family 25 member 20
  solute carrier family 25 member 24
  SRY-box transcription factor 2
  staufen double-stranded RNA binding protein 1
  sterol O-acyltransferase 1
  succinate dehydrogenase complex flavoprotein subunit A
  suppressor of cytokine signaling 1
  TAR DNA binding protein
  TATA-box binding protein associated factor 15
  TNFAIP3 interacting protein 2
  tonsoku like, DNA repair protein
  transcription factor CP2
  transforming growth factor beta 1
  transglutaminase 2
  translocase of outer mitochondrial membrane 20
  transmembrane protein 41B
  tripartite motif containing 25
  tripartite motif containing 28
  tubulin alpha 1a
  tubulin alpha 1c
  tubulin, gamma 1
  tumor necrosis factor
  tumor protein p53
  tyrosine kinase non receptor 2
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  ubiquitin conjugating enzyme E2 M
  ubiquitin like 4A
  ubiquitin specific peptidase 15
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  WW domain containing E3 ubiquitin protein ligase 2
  Yes1 associated transcriptional regulator
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.