- Gene Overview
- Interaction Network
- Sequence Verification
SLCO1B3, solute carrier organic anion transporter family member 1B3
-
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
-
Gene Synonyms (solute carrier organic anion transporter family member 1B3, liver-specific organic anion transporter 2, liver-specific organic anion transporter 3TM13, organic anion transporter 8, organic anion transporter LST-3c, organic anion-transporting polypeptide 8, solute carrier family 21 (organic anion transporter), member 8, HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8,)
- NCBI Gene ID:
28234
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>B3KP78
UNIPROT ID#>>Q9NPD5
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
solute carrier organic anion transporter family member 1B3 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|