GPD2, glycerol-3-phosphate dehydrogenase 2

GPD2, glycerol-3-phosphate dehydrogenase 2

• The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]

• Gene Synonyms (glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M, glycerol-3-phosphate dehydrogenase 2 (mitochondrial), mitochondrial glycerophosphate dehydrogenase, mitohondrial glycerophosphate dehydrogenase, mtGPD, testicular tissue protein Li 76, GDH2, GPDM, mGDH, mGPDH,)
• NCBI Gene ID: 2820
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53T76
  UNIPROT ID#>>P43304
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycerol-3-phosphate dehydrogenase 2 interacts with:

• 2'-5'-oligoadenylate synthetase 3
  anterior gradient 2, protein disulphide isomerase family member
  cullin 7
  dual specificity phosphatase 29
  elongation factor Tu GTP binding domain containing 2
  Fas associated factor family member 2
  glycerophosphodiester phosphodiesterase domain containing 5
  glycogen synthase kinase 3 beta
  HCLS1 associated protein X-1
  histone deacetylase 10
  mitochondrially encoded cytochrome c oxidase II
  neurofibromin 2
  neuropeptide Y receptor Y2
  neurotrophic receptor tyrosine kinase 1
  nuclear FMR1 interacting protein 1
  parkin RBR E3 ubiquitin protein ligase
  pleckstrin homology and RhoGEF domain containing G7
  pleckstrin homology domain containing A4
  protocadherin gamma subfamily B, 1
  proton activated chloride channel 1
  PVR cell adhesion molecule
  solute carrier family 39 member 4
  solute carrier family 39 member 8
  solute carrier family 8 member A3
  staufen double-stranded RNA binding protein 1
  succinate dehydrogenase complex iron sulfur subunit B
  trafficking protein particle complex 10
  ubiquinol-cytochrome c reductase complex III subunit VII
  vir like m6A methyltransferase associated
  WD repeat and FYVE domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.