FYB1, FYN binding protein 1

FYB1, FYN binding protein 1

• The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

• Gene Synonyms (ADAP, FYB, PRO0823, SLAP-130, SLAP130, THC3, FYN-binding protein 1, FYB-120/130, FYN-T-binding protein, FYN-binding protein, SLP-76-associated phosphoprotein, adhesion and degranulation-promoting adaptor protein, p120/p130,)
• NCBI Gene ID: 2533
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15117
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FYN binding protein 1 interacts with:

• BCAR1 scaffold protein, Cas family member
  BCL10 immune signaling adaptor
  caspase recruitment domain family member 11
  ENAH actin regulator
  Enah/Vasp-like
  FYN proto-oncogene, Src family tyrosine kinase
  lymphocyte cytosolic protein 2
  mitogen-activated protein kinase kinase kinase 7
  myelin basic protein
  NCK adaptor protein 2
  NRAS proto-oncogene, GTPase
  protein kinase C theta
  SH2 domain containing 1A
  src kinase associated phosphoprotein 1
  src kinase associated phosphoprotein 2
  SRC proto-oncogene, non-receptor tyrosine kinase
  ubiquitin conjugating enzyme E2 I
  vasodilator stimulated phosphoprotein
  WASP actin nucleation promoting factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.