CRAT, carnitine O-acetyltransferase

CRAT, carnitine O-acetyltransferase

• This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]

• Gene Synonyms (carnitine O-acetyltransferase, carnitine acetylase, CAT, CAT1, NBIA8,)
• NCBI Gene ID: 1384
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43155
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carnitine O-acetyltransferase interacts with:

• F-box and leucine rich repeat protein 4
  heat shock protein family A (Hsp70) member 8
  peroxisomal biogenesis factor 5
  regulator of G protein signaling 3

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