COL5A2, collagen type V alpha 2 chain

COL5A2, collagen type V alpha 2 chain

• This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]

• Gene Synonyms (collagen alpha-2(V) chain, AB collagen, collagen, fetal membrane, A polypeptide, type V preprocollagen alpha 2 chain, EDSC, EDSCL2,)
• NCBI Gene ID: 1290
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P05997
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collagen type V alpha 2 chain interacts with:

• EWS RNA binding protein 1
  F-box and WD-40 domain protein 11
  transglutaminase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.