COL3A1, collagen type III alpha 1 chain

COL3A1, collagen type III alpha 1 chain

• This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

• Gene Synonyms (collagen alpha-1(III) chain, Ehlers-Danlos syndrome type IV, autosomal dominant, alpha-1 type III collagen, alpha1 (III) collagen, collagen, fetal, collagen, type III, alpha 1, EDS4A, EDSVASC, PMGEDSV,)
• NCBI Gene ID: 1281
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P02461
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collagen type III alpha 1 chain interacts with:

• cullin associated and neddylation dissociated 1
  discoidin domain receptor tyrosine kinase 2
  Era like 12S mitochondrial rRNA chaperone 1
  fibroblast growth factor 7
  HtrA serine peptidase 1
  KRAS proto-oncogene, GTPase
  myelin associated glycoprotein
  myocilin
  platelet derived growth factor subunit A
  platelet derived growth factor subunit B
  procollagen C-endopeptidase enhancer
  secreted protein acidic and cysteine rich
  Sp1 transcription factor
  thrombospondin 1
  von Willebrand factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.