- Gene Overview
- Interaction Network
- Sequence Verification
CCL27, C-C motif chemokine ligand 27
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This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
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Gene Synonyms (ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27, C-C motif chemokine 27, CC chemokine ILC, IL-11 R-alpha-locus chemokine, IL-11 Ralpha-locus chemokine, chemokine (C-C motif) ligand 27, cutaneous T-cell attracting chemokine, skinkine, small inducible cytokine subfamily A (Cys-Cys), member 27, small-inducible cytokine A27,)
- NCBI Gene ID:
10850
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q5VZ77
UNIPROT ID#>>Q9Y4X3
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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C-C motif chemokine ligand 27 interacts with:
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