CDH2, cadherin 2

CDH2, cadherin 2

• This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]

• Gene Synonyms (cadherin-2, N-cadherin 1, cadherin 2, type 1, N-cadherin (neuronal), calcium-dependent adhesion protein, neuronal, neural cadherin, ACOGS, ARVD14, CD325, CDHN, CDw325, NCAD,)
• NCBI Gene ID: 1000
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RC42
  UNIPROT ID#>>P19022
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cadherin 2 interacts with:

• BOC cell adhesion associated, oncogene regulated
  cadherin 11
  cadherin 4
  catenin alpha 1
  catenin alpha 3
  catenin beta 1
  catenin delta 1
  catenin delta 2
  caveolae associated protein 3
  cell adhesion associated, oncogene regulated
  CREB binding protein
  discoidin domain receptor tyrosine kinase 2
  drebrin 1
  epidermal growth factor receptor
  erb-b2 receptor tyrosine kinase 2
  exocyst complex component 5
  F-box protein 45
  fibroblast growth factor receptor 1
  fibroblast growth factor receptor 4
  G protein subunit alpha 12
  G protein subunit alpha 13
  glucosidase alpha, acid
  glutamate ionotropic receptor kainate type subunit 2
  glutamate ionotropic receptor NMDA type subunit 1
  glutamate ionotropic receptor NMDA type subunit 2D
  isoleucyl-tRNA synthetase 2, mitochondrial
  junction plakoglobin
  kinectin 1
  leucine rich repeat containing 7
  lysosomal associated membrane protein 1
  methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
  mitochondrial ribosomal protein L23
  mitochondrial ribosomal protein L58
  nascent polypeptide associated complex subunit alpha 2
  neudesin neurotrophic factor
  neurotrophic receptor tyrosine kinase 1
  palmitoyl-protein thioesterase 2
  peripherin
  phosphoinositide-3-kinase regulatory subunit 1
  plakophilin 4
  pleckstrin homology domain containing A4
  polypyrimidine tract binding protein 3
  presenilin 1
  protein disulfide isomerase family A member 4
  protein tyrosine phosphatase non-receptor type 1
  pyruvate carboxylase
  RAB8B, member RAS oncogene family
  receptor like tyrosine kinase
  Rho GTPase activating protein 32
  ribosomal protein L14
  ribosomal protein L21
  ribosomal protein L3
  ribosomal protein L32
  ribosomal protein L8
  ribosomal protein S16
  ribosomal protein S26
  ring finger protein 4
  seryl-tRNA synthetase 2, mitochondrial
  signal sequence receptor subunit 4
  SLC9A3 regulator 1
  spectrin beta, non-erythrocytic 1
  S-phase kinase associated protein 1
  SPT5 homolog, DSIF elongation factor subunit
  transmembrane protein 256
  tropomyosin 4
  ubiquitin C
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.