MS4A1, membrane spanning 4-domains A1

MS4A1, membrane spanning 4-domains A1

• This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, CD20 antigen, CD20 receptor, leukocyte surface antigen Leu-16, membrane-spanning 4-domains, subfamily A, member 1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7,)
• NCBI Gene ID: 931
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P11836
  UNIPROT ID#>>A0A024R507
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

membrane spanning 4-domains A1 interacts with:

• atypical chemokine receptor 2
  autophagy related 16 like 1
  cAMP responsive element binding protein 3
  cAMP responsive element binding protein 3 like 1
  casein kinase 2 alpha 1
  casein kinase 2 alpha 2
  CD40 molecule
  ceramide synthase 4
  C-type lectin domain containing 14A
  family with sequence similarity 209 member A
  F-box and WD repeat domain containing 7
  Fc receptor like 3
  FYN proto-oncogene, Src family tyrosine kinase
  G protein-coupled receptor 42
  golgin, RAB6 interacting
  hydroxysteroid 17-beta dehydrogenase 11
  hydroxysteroid 17-beta dehydrogenase 13
  interleukin 7 receptor
  KASH domain containing 5
  lamin A/C
  LCK proto-oncogene, Src family tyrosine kinase
  leucine twenty homeobox
  LYN proto-oncogene, Src family tyrosine kinase
  major facilitator superfamily domain containing 14B
  major histocompatibility complex, class II, DR alpha
  major histocompatibility complex, class II, DR beta 1
  major histocompatibility complex, class II, DR beta 3
  major histocompatibility complex, class II, DR beta 4
  major histocompatibility complex, class II, DR beta 5
  MDM2 proto-oncogene
  mitochondrial translational initiation factor 3
  monocyte to macrophage differentiation associated
  receptor accessory protein 2
  receptor accessory protein 4
  ring finger protein 19B
  ring finger protein 5
  solute carrier family 10 member 1
  solute carrier family 10 member 6
  solute carrier family 18 member A1
  solute carrier family 35 member C2
  THAP domain containing 4
  thioredoxin related transmembrane protein 2
  translocator protein 2
  transmembrane protein 31
  transmembrane protein 72
  transmembrane protein 82
  transmembrane protein with metallophosphoesterase domain

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.