CCKBR, cholecystokinin B receptor

CCKBR, cholecystokinin B receptor

• This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]

• Gene Synonyms (gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK2 receptor, cholecystokinin-2 receptor, gastrin receptor, CCK-B, CCK2R, GASR,)
• NCBI Gene ID: 887
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E9PIC8
  UNIPROT ID#>>P32239
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cholecystokinin B receptor interacts with:

• ATPase cation transporting 13A2
  cholecystokinin B receptor
  germ cell-less 1, spermatogenesis associated
  kirre like nephrin family adhesion molecule 1
  neurotrimin
  protein kinase AMP-activated catalytic subunit alpha 1
  protein kinase AMP-activated non-catalytic subunit beta 1
  protein kinase AMP-activated non-catalytic subunit gamma 1
  protein tyrosine phosphatase non-receptor type 11
  PX domain containing serine/threonine kinase like
  THADA armadillo repeat containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.